Inherent Clinical Challenges
Bone Damage. Insufficient Fixation. Implant Instability & Loosening.
Implant fixation has its limitations and still poses1 a relevant clinical problem within the Orthopedic industry due to the inherent challenges of bone damage during implant insertion2, insufficient fixation and instability that can lead to implant loosening3.
Advanced Particle Based Simulation
Simulates complex bone structure subjected to high compression and crushing deformations resulting in micro bone fragments.
1. Widmer J, Aubin CE, van Lenthe GH, Matsukawa K. Innovations to improve screw fixation in traumatology and orthopedic surgery. Front Bioeng Biotechnol. 2022 Nov 25;10:1094813. doi: 10.3389/fbioe.2022.1094813. PMID: 36507265; PMCID: PMC9733944.
2. Steiner JA, Ferguson SJ, van Lenthe GH. Screw insertion in trabecular bone causes peri-implant bone damage. Med Eng Phys. 2016 Apr;38(4):417-22. doi: 10.1016/j.medengphy.2016.01.006. Epub 2016 Feb 23. PMID: 26920074.
3. Steiner JA, Christen P, Affentranger R, Ferguson SJ, van Lenthe GH. A novel in silico method to quantify primary stability of screws in trabecular bone. J Orthop Res. 2017 Nov;35(11):2415-2424. doi: 10.1002/jor.23551. Epub 2017 Mar 8. PMID: 28240380